Endocrine Abstracts

Introduction: NICE NG18 recommends level 3 carbohydrate counting from diagnosis for CYP diagnosed with Type 1 Diabetes. Our unit introduced in-patient level 3 carb counting from day 1 in 2015 in response to an audit demonstrating sub-optimal control in the first year of treatment.Methods: We carried out a longitudinal study of HbA1c in paediatric patients during the first year of diagnosis in two time periods, before and after the introduction of carb co...

Background: Islet transplant into the liver is a therapy for type 1 diabetes patients experiencing severe hypoglycaemia or impaired hypoglycaemic awareness. Widespread use is not currently considered due to the requirement for immunosuppression for the lifetime of the graft, and the attrition in graft function over the following 1-5 years. Following transplant into the liver, inflammation results in >60% islet loss, with few patients achieving insulin independence. The liv...